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I have no idea what you seek to achieve with this, but use try_files. That way, unless you are actively using http://foo.bar/index.php in your code, all requests will be evaluated at /.
Something like this:
location / {
try_files $uri $uri/ /index.php?$query_string;
}
If you are doing this because of duplicate content you can rest assure that Google don’t care all that much. Just be consistent in the way you link to your content.