Hi @drcmanansala,

It’s impossible to pinpoint the exact issue without checking the error logs first. The problem could be a million things from permissions,ownership to a problem with the configuration preventing phpMyAdmin from running normally.

I’ll recommend before you make any changes whatsoever, to check the Vesta error log, the Apache error log and see the exact reason behind the 500 internal server error.

Regards,
KDSys