Error in sending email

I have Vesta Control Panel on my Ubuntu 13.04 x32. When sending emails is launched the following error in the log ( /var/log/exim4/mainlog):

2014-04-08 11:41:59 1WW4bC-0008Om-0I == R=dnslookup T=remote_smtp defer (101): Network is unreachable 2014-04-08 11:41:59 1WWpOH-0004fL-2R == R=dnslookup T=remote_smtp defer (-53): retry time not reached for any host

The command: telnet 25

returns: Trying… Trying 2a00:1450:400c:c03::1a… telnet: Unable to connect to remote host: Network is unreachable

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I can connect to port 25 of Do you have any firewall setup? <br> <br>It would also be useful if you could post you exim conf: /etc/exim4/update-exim4.conf