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If you remove the “–from=default” it should work. This is because:
If you go into the API Logs on mandrill’s web site and search for “Mandrill-Python” you will see only the SMTP messages in the API Log.
looking at the Full Response section will give you some clues. When I was struggling with this I was seeing an error like this:
"reject_reason": "invalid-sender"
Make sure you include the from address as the first line of your mail message.
echo -e "From:example@example.com\r\nSubject: Test Mail\r\n\r\nThis is a test mail" | msmtp --debug --from=default -t myemail@gmail.com