currently unable to handle this request. HTTP ERROR 500

Dear Team,

I am unable to login to plesk pannel from Monday evening it gives error is currently unable to handle this request. HTTP ERROR 500 request.

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You would need to check your Plesk error log to see the actual error. To do so, you need to SSH to the server and then check the log at /var/log/sw-cp-server/error.log:

tail -100 /var/log/sw-cp-server/error.log

As described here a common cause of this problem is that you might have to set correct permissions to the following directories:

Set valid permissions for system directories:

chown root:root /tmp
chmod 1777 /tmp

chown root:apache /usr/sbin/suexec
chmod 4510 /usr/sbin/suexec

chown root:sw-cp-server /usr/lib64/sw-cp-server/sw-suexec
chmod 4710 /usr/lib64/sw-cp-server/sw-suexec

And finally restart sw-cp-server:

service sw-cp-server restart

Let me know how it goes. Regards, Bobby