Scale up as you grow — whether you're running one virtual machine or ten thousand.

From GPU-powered inference and Kubernetes to managed databases and storage, get everything you need to build, scale, and deploy intelligent applications.

This textbox defaults to using Markdown to format your answer.
You can type !ref in this text area to quickly search our full set of tutorials, documentation & marketplace offerings and insert the link!
These answers are provided by our Community. If you find them useful, show some love by clicking the heart. If you run into issues leave a comment, or add your own answer to help others.
Sorry for the late reply. With those persistent connections it’s possible that you are running out of listeners (with all the slots full with persistent connections and the short term php ones as well new clients may be getting denied or dormant connections freed up).
I would recommend reviewing my.cnf (in /etc/mysql) to see what your max_connections variable is set to. With the persistent connections, check the wait_timeout value in case MySQL is timing out these connections when they are idle.