You don't require nginx to be installed to run Ghost and it can easily be replaced with Apache or run standalone. nginx is preferred as it's more focused on proxy/static file hosting than Apache and is for those reasons perfect for use with Ghost. To use it with Apache, simply setup a virtual host that reverse proxys to your Ghost blog in your Apache config so that any requests on that virtual host will go through Apache to your Ghost blog.

Ghost runs its own Node.js-based webserver, so you can use any program that supports reverse proxying in place of nginx.

It is possible to use Apache's mod_proxy extension to proxy requests to the built-in Ghost webserver. Take a look at the following tutorial:

• How To Use Apache HTTP Server As Reverse-Proxy Using mod_proxy Extension.

Thanks :D