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When it comes to setting up a fully functional, working e-mail server, ideally you need to set it up on it’s own Droplet/Server – independent of your web server. There’s a lot that goes in to running a mail server, specifically ensuring that SPF, DKIM and potentially DMARC are working as intended as those are three things that are going to keep your e-mail out of the junk/spam folders (without them, mail is going to end up in junk/spam).
If you’re dead-set on running your own mail server, I’d take a look at MailCow. It’s relatively easy to set up and use.