First of all change this line

<Directory /home/clerck/Downloads/>
Options Indexes FollowSymLinks
AllowOverride None
Require all granted
</Directory>

to this line

<Directory /media/clerck/Downloads/>
Options Indexes FollowSymLinks
AllowOverride None
Require all granted
</Directory>

And if it doesn't work try to add those lines at /etc/apache2/apache2.conf

<Directory /media/clerck/>
Options Indexes FollowSymLinks
AllowOverride None
Require all granted
</Directory>

sorry i miss with the file name, it didn't work untill i apply this command
sudo chown -R www-data:www-data /media/clerck/Downloads

i face another issue when i try to use the real Directory, i change it on both files
/etc/apache2/apache2.conf && /etc/apache2/sites-enabled/000-deftault.conf
but the error appear again and "chown -R www-data:www-data " didn't solve the issue
this from log
clerck@clerck:/media/clerck/5b7ea25c-624b-4048-9c50-d3e76c9dc2e6/repos$ tailf /var/log/apache2/error.log
[Mon Jun 05 16:50:02.872782 2017] [core:error] [pid 17501:tid 140372126148352] (13)Permission denied: [client 127.0.0.1:50530] AH00035: access to / denied (filesystem path '/media/clerck/5b7ea25c-624b-4048-9c50-d3e76c9dc2e6') because search permissions are missing on a component of the path

this Directoty on external Hard Drive by the way|
so now it's working on /home but didn't work on the external hard
permission changed to 755 but still the same