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I actually finished solving the exact same issue right now with a bit of help from a support person.
First of all let me say this, the support (so far) has been AMAZING and need I say FAST.
Once the support person indicated to me that IPV6 was causing the issue, I immediately searched Google and found this lovely thread. If this thread didn’t exist, I’d probably still have an opened ticket, but instead, @kamaln7 's post worked flawlessly.
Thanks once again @kamaln7 for helping the community out. I owe you one.
I was also using the MailGun API to send emails and IPv6 was the reason, it was giving the Gateway Timeout Error.
Error resolved when enabled precedence in /etc/gai.conf:
precedence ::ffff:0:0/96 100