I have created a CentOS 6.5 x64 droplet with LEMP installed as described here: https://www.digitalocean.com/community/articles/how-to-install-linux-nginx-mysql-php-lemp-stack-on-centos-6 It is working fine, http://vps.eletter.gr/info.php. I have ported a sample CodeIgniter application (https://github.com/scoumbourdis/grocery-crud/archive/v1.4.1.zip) under http://vps.eletter.gr/gc141/ but when I try to click to any of the links it returns 404 error. I also tried to install FUEL CMS http://vps.eletter.gr/fuel/install but again it comes up with a 404 error where when on http://vps.eletter.gr/fuel works fine. Obviously it has to do with the nginx conf file but I have tried many options without luck! The /etc/nginx/conf.d/default.conf file is: server { listen 80; server_name vps.eletter.gr; location / { root /usr/share/nginx/html; index index.php index.html index.htm; } error_page 404 /404.html; location = /404.html { root /usr/share/nginx/html; } error_page 500 502 503 504 /50x.html; location = /50x.html { root /usr/share/nginx/html; } # pass the PHP scripts to FastCGI server # location ~ \.php$ { root /usr/share/nginx/html; fastcgi_pass unix:/tmp/php5-fpm.sock; fastcgi_index index.php; fastcgi_param SCRIPT_FILENAME $document_root$fastcgi_script_name; include fastcgi_params; } }