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My 2 cents: it happened to me when having a bad line in the .conf file (in my case a comment was uncommented :P )
Everything was working fine and suddenly this issue appeared +1. I can’t find what’s wrong 😢
I think it might be some issue with Digital Ocean service. After this reply for several minutes, all connections worked again, I didn’t make any changes on my server.
I have the same problem since this morning. A quick scan on nmap revealed that my port 80 is being closed on the remote server. I have advised the support team and waiting for a response.
Hope this helps,