Saying that "Webmin/Virtualmin" are not user friendly is a colossal understatement. It probably does way more than what you need, and it will probably take less time to learn how to configure Apache by hand than it will to learn how to use the control panel. It's just page after page of incomprehensible fine-grained attributes and no help for the uninitiated. I wouldn't recommend it if you're not already an experienced Xnix admin and understand how to do things by hand.
Vesta is at the other extreme. I like it quite a bit, but bear in mind that it's very simple. You can easily get a website up and running with it, but it misses a few features that I'd love to see (upgrading PHP or MySQL versions, for example).