FlaskApp won't apply mod rewrite from htaccess

Hi there, does anyone knows if there is anything -special- that has to be done for my FlaskApp to apply the url-rewrite pattern from htaccess? I have a fully functional FlaskApp with mod rewrite enabled, and a correct RegEx rule (tested, works) but it simply won’t be applied to the URLs.

This is my htaccess:

RewriteEngine On
RewriteRule ^average_temperatures/([^/.]+)/([^/.]+)/([^/.]+)/?$ average_temperatures?city1=$1&city2=$2&city3=$3

FlaskApp.conf:

<VirtualHost *:80>
                ServerName weather-averages.co.uk
                ServerAdmin petrol.bears@gmail.com
                WSGIScriptAlias / /var/www/FlaskApp/flaskapp.wsgi
                <Directory /var/www/FlaskApp/FlaskApp/>
                        Order allow,deny
                        Allow from all
                </Directory>
                Alias /static /var/www/FlaskApp/FlaskApp/static
                <Directory /var/www/FlaskApp/FlaskApp/static/>
                        Order allow,deny
                        Allow from all
                </Directory>
                ErrorLog ${APACHE_LOG_DIR}/error.log
                LogLevel warn
                CustomLog ${APACHE_LOG_DIR}/access.log combined
</VirtualHost>

<VirtualHost *:80>
		ServerName www.weather-averages.co.uk
		Redirect permanent / http://weather-averages.co.uk/
</VirtualHost>

and 000-default.conf

VirtualHost *:80>

	ServerAdmin webmaster@localhost
	DocumentRoot /var/www

	ErrorLog ${APACHE_LOG_DIR}/error.log
	CustomLog ${APACHE_LOG_DIR}/access.log combined

	<Directory /var/www/>
			Options Indexes FollowSymLinks MultiViews
			AllowOverride All
			Order allow,deny
			allow from all
	</Directory>

</VirtualHost>

I enabled the log for this rule, and I see that the rule is applied, but to all other things, but the URL I want:

[perdir /var/www/] applying pattern '^average_temperatures/([^/.]+)/([^/.]+)/([^/.]+)/?$' to uri 'index.pl'

[perdir /var/www/] applying pattern '^average_temperatures/([^/.]+)/([^/.]+)/([^/.]+)/?$' to uri 'index.cgi'

[perdir /var/www/] applying pattern '^average_temperatures/([^/.]+)/([^/.]+)/([^/.]+)/?$' to uri ''

And so on… Any help is greatly appreciated.